INNOVATION CENTER FOR GENE MEDICINE

충남대학교 신약전문대학원 & 대전테크노파크 바이오센터

CRISPR/Cas9 라이브러리 스크리닝 서비스

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Lentiviral Cas9/sgRNA Library Screening Service

  • Lentiviral
    sgRNA library
  • Infection of
    target cells
  • Screen assay
  • Readout NGS &
    BI analysis
  • Hit ID
1. Loss-of-function screening by gene knock-out is a powerful tool for systematic analysis in mammalian cells
  • Genome-wide functional interrogation (e.g., signal transduction pathways)
  • Drug discovery (e.g., target identification and drug mechanism studies)
2. Identify Genes Essential for Growth and Proliferation
  • Identify genes essential for cell viability
  • Find targets that increase cell sensitivity to compounds or treatments
  • Look for synthetically lethal interactions with known genetic lesions
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